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Hi BW, I am not sure why it is called a millennium trial I must check and see how long the trial has been going. Yes we do have a dedicated nurse and we were given her direct number to use. Mr Mog will be seen each month and have scans every 2 months while on this trial. A friend on Ravelry informed me that they can work round stuff such as the infection so it wouldn't necessarily preclude Mr Mog from going on the trial. My trouble now is that I've been googling(as you do) and some earlier trial results are in. It seems that of 26 on an earlier trial, 23 experienced side effects. I haven't told Mr M yet, I need to do more research and at this stage I don't want to be giving him possibly false information if for example they have altered dosage or something similar. He is worried enough over going into the trial. But as I wrote earlier they really haven't given us any feasible alternatives.